Homewood Cemetery is a historic, nonsectarian burial ground in Pittsburgh, Pennsylvania, United States. It is located in Point Breeze and is bordered by Frick Park, the neighborhood of Squirrel Hill, and the smaller Smithfield Cemetery.

It was established in 1878 from William Wilkins' 650-acre (2.6 km2) estate, Homewood.

Notable interments

• David Lytle Clark (1864–1939), businessman, creator of Clark Bar & Zagnut
• Bertha Lamme Feicht (1869-1943), First female engineering graduate from Ohio State University and first female engineer to be employed by Westinghouse.
• William Flinn (1851–1924), politician
• Henry Clay Frick (1849–1919), industrialist, founder of the South Fork Fishing and Hunting Club
• Childs Frick (1883-1965)- Anthropologist
• Helen Clay Frick (1888–1984), philanthropist
• Henry P. Ford (1837–1905), Mayor of Pittsburgh, 1896–1899
• Erroll Garner (1921–1977), jazz pianist and composer
• Teenie Harris (1908–1998), photographer
• H. J. Heinz II (1908–1987), industrialist
• H. John Heinz III (1938–1991), United States Senator
• George Hetzel (1826–1899), portrait and landscape painter
• Michael Late Benedum (1869-1959) businessman, co-founder of Benedum-Trees Oil Company
• John Barrett Kerfoot (1816–1881), first Episcopal Bishop of Pittsburgh
• Perle Mesta (1889–1975), Ambassador to Luxembourg 1949-53, and a noted Washington, D.C. socialite during Eisenhower and Nixon eras.
• Alvin P. Shapiro (1920–1998), a physician and educator
• Stephen Varzaly (1890–1957), priest, journalist, and cultural activist
• Ernest T. Weir, founder of Weirton Steel and National Steel Corporation
• William Wilkins (1779–1865), U.S. Senator

Sports figures

• Chuck Cooper (1926–1984) First African-American to be drafted into the NBA
• Bill Bishop (1869–1932, professional baseball player
• Pie Traynor (1899–1972), baseball Hall of Famer
• Jock Sutherland (1889–1948), football coach